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GIS is becoming increasingly valuable in biology by making new sources of data available and opening up complementary avenues for research. In the University of Alberta's Department of Biological Sciences, there are approximately 80 graduate students--supervised by almost 20 professors--who are currently applying GIS technology to improving or developing alternative methods used in their organism, ecosystem, and other ecology-related investigations. Innovative solutions for understanding spatial relationships while adhering to the unique criteria of biological phenomena are often required in these diverse and large research projects. Methods on instructing the graduate researchers who are too busy for mainstream education, how to manage a Departmental research lab, as well as some GIS solutions to sample research problems will be presented.